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(2018): Acetyl-L-carnitine supplementation and the treatment of depressive symptoms: a systematic review and meta-analysis : Denne meta-analyse samlede randomiserede kontrollerede studier af ALCAR ved depression, srligt hos ldre, og fandt en signifikant gennemsnitlig effekt p depressive symptomer i de undersgte populationer

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However, certain conditions like pregnancy may result in increased excretion of L-carnitine, potentially increasing the risk for deficiency