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in the real world, the risk stems from how its sold, dosed, and used
Metformin recipients also had significantly higher levels of homocysteine and methylmalonic acid (markers of B12 deficiency) and significantly worse scores on standardised clinical assessments of the severity of neuropathy
From these results we can assume ozone therapy influenced positively the synthesis and release of cytokines (14,15) in such away that a change from Th2 to Th1 [IL-2, IFNg] pattern occurs, reducing the production of asthma mediators [IgE, HLA-DR, etc]
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