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Surgical procedures: Gastric bypass surgery or removal of parts of the small intestine can impair B12 absorption

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Nasal formulations for drug administration and characterization of nasal preparations in drug delivery
Its working mechanism is allosteric facilitation of HGF/c-Met signaling: Dihexa binds HGF with high affinity (reported K d ~65 pM in the original work) and is proposed to potentiate HGF dimerization and c-Met phosphorylation at subthreshold endogenous HGF concentrations
