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Moreover, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor-mediated Na + /Cl influx further disturbs osmotic balance, contributing to cytotoxic edema, a process blocked by AMPA antagonists (e.g., perampanel) in rodent models [139, 140]

Guron, and Michael Maroules Comparison of checkpoint inhibitorbased regimens as first-line therapy in advanced hepatocellular carcinoma: A Frequentist Network meta-analysis of randomized clinical trials

Therefore, selenium deficiency is associated with thyroid dysfunction and increased risk of thyroid autoimmunity and nodules [65], a condition further aggravated by the fact that concurrent iodine and selenium deficiency is rather common [66, 67]