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642 In a multicenter, randomized, double-blind, placebo-controlled phase-3 clinical trial conducted in China, acetyllevocarnitine hydrochloride treatment for 24 weeks significantly improved symptoms and somatosensory symptoms in patients with DPN, with a treatment effect of 65% higher than placebo

Nomoto M, Thompson PD, Sheehy MP, Quinn NP, Marsden CD

Intriguingly, melatonin supplementation improves oxidative DNA capacity (measured as urinary excretion of 8-OHdG) in NS workers, suggestive of a possible preventive intervention 30

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Application of BSO-OxMal , BSO-OxOAc or oxaliplatin significantly reduced tumor volumes as compared to solvent controls during the first two weeks of treatment without significant differences between the three metal drugs (Fig