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Biofactors 2009

Regulating TAM iron metabolism within the TIME, specifically by promoting iron uptake and storage in M2-type macrophages while inhibiting iron release, allows iron accumulation in TAMs to enhance ROS production, increase p300/CBP acetyltransferase activity, and promote p53 acetylation

M., Fedele, G., Martinelli, I., Gianferrari, G., Simonini, C., Fini, N., Ghezzi, A., Caputo, M., Sette, E., Vacchiano, V., Zinno, L., Anceschi, P., Canali, E., Vinceti, M., Ferro, S., Mandrioli, J., & ERRALS study group

22.1 8.9 mol/L), whereas no such significant changes were observed in the control group (Table 2)

Breast Cancer Research