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PMID: 73 JinDHuiYLiuDLiNLengJWangGet al

GHK-Cu interacts with both phases, but not equally

The extract demonstrated its potential to mitigate oxidative stress, restore antioxidant defenses, and suppress inflammation through the activation of the Nrf2/HO1 pathway

Ferroptosis is characterised by increased reactive oxygen species (ROS), lipid peroxidation, iron accumulation, as well as depletion of glutathione (GSH) [47], and it has been seen in chronic bone disorders, such as OA [48-50]

But it stressed that dose-response relationships were not established and that there is insufficient clinical safety information to characterize BPC-157's human safety profile with no studies administering it to humans by the proposed routes