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More specifically, Nrf2 activation affects the expression of over 200 different genes, all of which contain the code for cellular defence against oxidative stress and ageing
J., & Dreher, A
Cells, Blood Substitutes, Biotechnol., 2012, vol
It also improved the proliferative and secretory functions of fibroblasts and reversed morphological abnormalities of senescent cells (such as flattened cell shape, enlarged volume, and nuclear pyknosis)
