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About this article Cite this article Agarwal, A., Aponte-Mellado, A., Premkumar, B.J

Varani, J

10.1016/j.cell.2011.04.013 88 WangM.HuJ.YanL.YangY.HeM.WuM.et al (2019)

Although oxidative stress, mitochondrial damage, and cell death involved in the pathogenesis of APAP hepatotoxicity have been reported [25], accumulating studies on the pathogenesis of APAP hepatotoxicity indicate that subsequent inflammatory responses of the immune system critically determine the severity and outcome of disease [26, 27]

They found that quercetin improves lipid metabolism and intestinal flora while reducing ferroptosis markers (total iron, Fe2+, MDA, and ROS)
