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melanotic macule skin histopathology Transformation of a benign oral pigmentation to primary oral melanoma Guidelines for diagnosis and pathological
Description
When tissue does not receive or stops receiving oxygen, it dies

So I would suggest that there isnt a great deal of similarity between the two cases. The answer still feels unsatisfactory and frankly puzzling

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And after several minutes my lips were noticeabley plumper and voluputous

If a patient presents with numerous keratoses and it is impractical to treat all of them, target symptomatic, hyperkeratotic (Figure 4) or thickened lesions with cryotherapy as these lesions have a greater risk of transforming to SCC
