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However, certain populations are, at an increased risk, including individuals with alcoholism, pregnant women, and those adhering to restricted diets, such as those diagnosed with phenyl-ketonuria or small bowel disorders associated with malabsorption (, )

Abbreviations ER endoplasmic reticulum IMM inner mitochondrial membrane GCL glutamate-cysteine ligase GPx glutathione peroxidases GR glutathione reductase Grx Glutaredoxin GS glutathione synthetase GSH reduced glutathione GSSG oxidized glutathione GSH/GSSG ratio between reduced and oxidized glutathione GST glutathione S-transferase MOM mitochondrial outer membrane mtGSH mitochondrial glutathione OGC 2-oxoglutarate carrier ROS reactive oxygen species SLC soluble carrier protein TR thioredoxin reductase Trx Thioredoxin xCT cystine/glutamate antiporter SLC7A11 Footnotes Conflicts of interest J.W

Receive Your Sublocade Injection Once you and your doctor have decided it is safe for you to switch to Sublocade, it is time to receive your first injection

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Alzheimers Research & Therapy (2022) 14:23 brain GSH is aected by many pre- and post-mortem fac- tors and changes quickly after death [19, 20]