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Zonisamide shares structural features with topiramate and has a similar mechanism of action to inhibition of carbonic anhydrase inhibition, with potential benefits in migraine prevention, weight loss, and decreased alcohol use

Additionally, NAC exhibited anti-inflammatory actions by reducing IL-6 and TNF- expression at both mRNA and protein levels and by enhancing GPx gene transcription

Cognitive function or cognition as used herein refers to a range of high-level brain functions, including but not limited to: the ability to learn and remember information

34 Consequently, turnover of 5,10-methyleneTHF via the TYMS enzyme is proposed to be greater in 3R3R individuals, with a decrease in this vitamer and an increase in homocysteine levels previously observed in such individuals

t = 1.29, p = 0.20) (see Supplementary Table 1), where the NAA peak-area SNR is defined as the ratio of the time-domain amplitude of the NAA CH 3 singlet divided by the standard deviation of the noise measured in the last 32 points of the time-domain signal