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More research is needed in this area though The World Health Organization in its 2007 report on the safety and efficacy of Kava noted: 2.1.3
Cheng F., Lu W., Liu C., et al., A Genomewide Positioning Systems Network Algorithm for in Silico Drug Repurposing, Nature Communications 10, no
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Some include the alteration of drug targets, expression of drug pumps, expression of de-toxification mechanisms, reduced susceptibility to apoptosis, and increased ability to repair DNA damage, among others
10.1615/intjmedmushr.v6.i2.60 50 HsuC.-C.HuangY.-L.TsaiS.-J.SheuC.-C.HuangB.-M
