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As a result, they likely require higher doses of NAD + precursors when exposed to genotoxicity [449]

2 After IV administration of Lcarnitine in doses ranging from 20 to 100 mg/kg, the initial volume of distribution was 0.20.3 L/kg, the terminal halflife ranged from 4 to 23 h and plasma concentrations of Lcarnitine returned to baseline within 1224 h