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However, in spite of its ability to trigger MOR regulation, exposure to morphine induced superactivation of the striatal cAMP cascade [69], suggesting that MOR desensitization when associated to this effector might not be enough to completely avoid cellular compensatory mechanisms

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al., 2017) shows that ABA that is received for longer periods of time and that is higher in intensity more hours of service per week is more effective than short-term, less intensive ABA