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Understanding the pathogenesis involved in Parkinsons disease and potential therapeutic treatment strategies

It allows systematic data acquisition which is comparable in the follow-up of patients and also, their inclusion in research studies

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In the human condition Fanconi Anaemia, metabolic ROS were shown to induce DNA damage in hematopoietic stem cells (HSCs) when they start cycling to exit quiescence, which impairs blood production in FancA / mice 51

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