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Redoxin redux: emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation

I In macrophages, TIM-3 signaling alters iron metabolism, further promoting oxidative stress

The potential for toxicity is incredibly low, and the risk of side effects (other than an allergic reaction, which is also low) are mostly confined to things like minor skin irritation

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Abdominal, back, or extremity pain grows in intensity over a 24- to 48-hour period, which may lead the clinician to consider appendicitis or an acute abdomen