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Serious B12 deficiency may cause anemia and nerve damage

One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition

[9] The doses in this compounded injection are much lower than those therapeutic megadoses, but still higher than typical dietary intake

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Payers monitor modifier 25 usage patterns and may request documentation review if the rate exceeds their benchmarks