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Two randomized controlled trials published in JAMA Network Open by Imperial College London (2022 and 2023) found that kisspeptin significantly changed brain activity in key sexual processing regions in both women and men with low libido, with no reported adverse effects in either study

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10.1186/s13011-015-0006-5 [DOI] [PMC free article] [PubMed] [Google Scholar] Shankara-Narayana N., Yu C., Savkovic S., Desai R., Fennell C., Turner L., et al