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Description
These effects are usually mild and resolve quickly

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs

Michalon et al., 2014

STIM2 (stromal interaction molecule 2)mediated increase in resting cytosolic free ca 2+ concentration stimulates PASMC proliferation in pulmonary arterial hypertension

Recommendation: No b12 supplementation needed at start
