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The glomerular function was evaluated by determining serum and 24-h urine creatinine, urinary albumin in the first-morning sample, and by estimating glomerular filtration rate (eGFR) with the CKD-EPI formula 54

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Accumulating evidence has demonstrated that excessive inflammatory responses can significantly affect the normal function of NP cells and thus contribute to IDD development 4,32

You L, Zha D, Anslyn EV (2015) Recent advances in supramolecular analytical chemistry using optical sensing