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Liu J, Shen JX, Wen XF, Guo YX, Zhang GJ

Macrophage Polarization Your immune system contains macrophages that can either promote inflammation (M1 type) or support tissue repair (M2 type)

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The three most extensively studied peptides in this category are: BPC-157 (Body Protection Compound-157) a stable gastric pentadecapeptide originally identified in gastric juice TB-500 (Thymosin Beta-4) a naturally occurring 43-amino acid actin-regulating peptide GHK-Cu (Copper Tripeptide-1) a copper-binding tripeptide with matrix remodeling properties Each of these peptides operates through distinct molecular mechanisms, yet they share a common theme in their ability to influence cellular processes relevant to tissue repair and structural regeneration

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity