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In the HCC ACLY KO cells, we quantified acetyl-CoA in the presence or absence of acetate, finding that acetyl-CoA abundance is elevated in ACLY KO cells in the presence of acetate and decreases back to that in WT cells in its absence (Figure 1F)

Gao QQ, Chen JH, Chen Y, Song T, Dai YT

kidney involvement with elevated serum creatinine, decreased glomerular filtration rate, hematuria, urinary sediment changes and even the need for renal replacement therapy

Niwa, T
