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PMID 16520826

For peroxiredoxins, little data is available, but elevated levels of several isoforms were measured in plasma of individuals with T2D [267], and prevention of apoptosis of pancreatic-beta cells was reported [272]

Through trans-signaling, IL-6 activates the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, enhancing NF-B and leading to increased production of ROS and pro-inflammatory cytokines [29]