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NF- is regulated by recognized signaling pathways (triggered by IL-1, TNF-, ROS, and LPS) and noncanonical signaling pathways, which are triggered by inflammatory stimuli across IKK
The constitutive expression of mIDO2 was detected in many organs at the protein and mRNA level (see Supplementary Table S1) and additionally, mIDO2 mRNA was upregulated in dendritic cells and mesenchymal stem cells treated with IFN- [132]
