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It should be clarified that although the contribution of immune cells to metabolic diseases is mainly concentrated in AT, an effective source of such inflammation also exists in the liver, intestines, and other metabolic regulatory tissues, promoting the production of inflammation and obesity throughout the body through the circulation (131)

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Predrag Sikiric, Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia [email protected]

We would not expect a close match to the clinically observed percentage changes because we are comparing intracellular model changes to blood measurements

NADPH oxidase regulates Paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis