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With aging, the number of Leydig cells per testis remains unchanged, but these cells may exhibit a reduced capacity for testosterone synthesis, resulting in an age-related decline of serum testosterone levels [8, 9]

doi: 10.1016/j.molimm.2015.04.002 16 TaiYTMayesPAAcharyaCZhongMYCeaMCagnettaAet al
1999;276(3 Pt 1):G71927
The significant caution is that the oncogenic potential of sustained c-Met activation remains unstudied in long-term models

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