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A path to translation: How 3D patient tumor avatars enable next generation precision oncology

Berginer VM, Shany S, Alkalay D, Berginer J, Dekel S, Salen G, Tint GS, Gazit D
The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states

Although NRF2 activation is beneficial in diseases characterized by oxidative stress, including neurodegenerative, cardiovascular, and metabolic disorders [8, 9], in cancer, its persistent activation can be maladaptive

Rauch F, Glorieux FH
