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A double blind RCT by Orris et al 37 that included 30 male subjects with moderate acne demonstrated no statistically significant differences in papule, pustule, or comedone count in groups treated with oral zinc versus lactose placebo for eight weeks

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[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Coogan PF, Wise LA, OConnor GT, et al

Whole blood was collected from the sodium heparin tubes and the remaining heparinized blood was centrifuged at 1500 g for 10 min at 4C and serum tubes were centrifuged at 1500 g for 10 min at 25C after clotting