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Unlike natural amylin, which has a very short half-life, cagrilintide's molecular structure allows for once-weekly administration, making it considerably more practical for research applications

Using density functional theory calculations, the catalytic cycle of the ruthenium catalyst was predicted

Most patients find the procedure well tolerated

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In this work, we explore how the brain-gut axis, immune activation, microbial dysbiosis, intestinal barrier dysfunction, bile acid malabsorption and serotonin signalling interplay to drive IBS