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Each possesses a formidable reputation, backed by a growing body of preclinical data suggesting significant potential

The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)

JAMA Psychiatry 72: 778

References Zhao W, Xu Z, Cao J, Fu Q, Wu Y, Zhang X, Long Y, Zhang X, Yang Y, Li Y, Mi W

Bitters and Digestive Stimulants: Gentian, ginger, and other digestive bitters that stimulate stomach acid production and improve digestion, potentially alleviating GERD symptoms caused by hypochlorhydria