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The CASTA Failure: The 2012 CASTA triala large, multicenter, double-blind study of Cerebrolysin for acute ischemic stroke in Asia (n=1,070)failed to meet its primary endpoint, showing no significant benefit over placebo

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The development of a biomimetic scaffold comprises different aspects, such as the fabrication technique, which determines the macro- and microarchitecture of the scaffold, the material used for scaffold fabrication and the inclusion within the scaffold of bioactive molecules or other stimulating factors to promote the formation of a functional tissue (Figure 1)

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Effects of eight-week supplementation containing red orange and Polypodium leucotomos extracts on UVB-induced skin responses: a randomized double-blind placebo-controlled trial