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Though the group reported appreciable 1000:1 selectivity for hMC4R affinity compared to hMC1R affinity, functional cAMP assay results were only reported for hMC4R (EC 50 = 88 nM, E max = 85%), seen in Table 1 (55)

Datta R

124(11): 164955 Njoo MD, Westerhof W, Bos JD, et al
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