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The IL-8 signaling pathway is involved in neuroinflammation, resulting in progressive neural sensitization in OIPN model [82]

doi: 10.1152/ajpendo.00132.2005

Transforming growth factor-beta 1 acts cooperatively with sodium n-butyrate to induce differentiation of normal human keratinocytes

Overall, resveratrol exerts multi-faceted anti-cancer effects by modulating tumor immunity (e.g., boosting cytotoxic T cells and NK cells), reversing drug resistance (via down-regulating EGFR and P-gp), inducing autophagy and ferroptosis, and arresting cell cycle progression while promoting apoptosis