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Reactive metabolites, formed via drug metabolism in the body, are electrophilic species which can bind covalently to macromolecules such as proteins and DNA, affecting their function and potentially leading to toxicity

doi: 10.1007/s11356-021-17830-7

While published results highlight SFNs therapeutic potential, limited sample sizes and inconsistent outcomes underscore the need for more extensive, stratified trials

Lipotropic nutrients are a class of natural ingredients that play an important role in the bodys use of fat

Compared to NAFLD patients, NASH patients exhibit reduced levels of FXR, SHP, and NTCP proteins, and FXR plays a protective role in the progression from NAFLD to NASH ( Allobaculum and Bifidobacterium (Wang et al., 2024b)