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The temporary employment of additional chaperones in response to oxidative stress provides an efficient mechanism to specifically counteract and resist the strong oxidizing properties of MPO-derived hypohalous acids during infection or inflammation

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Another study identified the EGFR-MYC-TXNIP axis as an important regulator of the TNBC metabolism and demonstrated the association between the EGFRhigh-MYChigh-TXNIPlow gene signature with aggressive glycolytic metabolism and a poor survival rate in TNBC (22)

Finally, regional differences in ketone body metabolism and downstream neuroprotective effects of the ketogenic diet likely exist and were not evaluated in this pilot study