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Sacrifice was achieved under anesthesia (3% isoflurane at 0.5 L/min of O 2 ) after a 4 h fast to standardize the feeding status of each animal
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Following three months of uninterrupted administration, the retinal tissue samples were collected for subsequent analysis
The activation of VEGFR-1 leads to inflammation, while the activation of VEGFR-2 leads to angiogenesis (Farghaly et al., 2021)
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