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Mitochondrial contribution to Parkinsons disease pathogenesis

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E., Danai, L

The transformation of cholesterol into bile acids in the liver, via the classical pathway that produces 12-hydroxy bile acids (cholic acid) catalyzed by CYP8B1 and the alternative pathway that yields non-12-hydroxy bile acids (chenodeoxycholic acid) catalyzed by CYP7B1, constitutes the primary cholesterol metabolism route (136)