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Notably, as a result of reduced production of chemokines including Ccl2 and Cxcl10, which recruit monocytes to the site of inflammation, adipose tissue expression of M1 macrophage marker Cd11c was decreased in eWAT from Cpt1b m/ mice compared to control Cpt1b fl/fl mice (Fig

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The compound's selectivity profile minimizes concerns about off-target effects, but investigators should consider potential interactions with other NAD+-modulating interventions or compounds that affect methylation metabolism

No cardiovascular signals

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