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Free Radical Research 2010

25, 26 There is no evidence that melatonin causes tolerance, dependence, withdrawal or rebound insomnia

glutathione may degrade quickly when exposed to light or air

If the sulfation pathway is defective, as has been shown in autism, and/or there is impaired glucuronidation, acetaminophen will be increasingly converted to the alternative metabolic routes, increasing production of its more toxic compounds NAPQI and AM404

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