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Increased interest in health, disease prevention and treatment, aging populations, urbanization, and public awareness of nutrition have led to the development and introduction of several health-benefitting products namely functional foods, herbal medicines, and their products [1]

At times, AuNPs that seem to be nontoxic in cell culture-based experiments end up being toxic in animal experiments

(PubMed) Cardoso CR, Souza MA, Ferro EA, Favoreto S, Jr., Pena JD

Such alterations activate peripheral and central immune-inflammatory responses, compromise blood-brain barrier integrity, and disrupt neuroimmune cytokine signaling

Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment