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Nussbaumer, S

Balkrishna A, Sharma N, Srivastava D, et al

500,000 cells were seeded in 6 well plates and grown overnight before adding treatments

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Thus, it has been determined that increased intracellular calcium and calmodulin activation in the lens can activate connexin hemichannels (essential for mediating communication and the exchange of the molecules between cells, as well as between the intracellular and extracellular environments) in lens fibers, disrupting their proper homeostasis and consequently favoring cataract development [45]
