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The hexabody did not compete in vitro with Daratumumab or Isatuximab, but strongly inhibited the cyclase activity of the target

At position fifteen, the amino acid histidine (His) is replaced with a modified amino acid called D-Phenylalanine (D-Phe)

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Kraus D., Yang Q., Kong D., et al

Metabolic theory of septic shock

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