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Description
Food and Drug Administration (FDA) defined adaptogens as a new class of metabolic regulators that demonstrated the ability to increase an organisms ability to adapt to its environment and mitigate external damage [63]

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GABAergic transmission in the rat paraventricular nucleus of the hypothalamus is suppressed by corticosterone and stress

The leading causes of histamine intolerance are too few enzymes needed to break down histamine and/or too much histamine production

Generally mild and reversible with dose reduction or discontinuation
