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The trial data (STEP 4) supports continued therapeutic dosing
Cell 88:131141 [DOI] [PubMed] [Google Scholar] Fan W, Ellacott KL, Halatchev IG, Takahashi K, Yu P, Cone RD 2004 Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system
Supplementary Table S1), in line with the lifespan effect of excess dietary fat in mice 34
It may indicate a potential health issue, especially if it persists or is associated with symptoms
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