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J Nutr Sci Vitaminol.(Tokyo) 2001;47(6):378-384

In general, the presence of substantial neurological/psychiatric dysfunction during vomiting episodes can be an important marker to the potential presence of an underlying metabolic disorder, including OTC deficiency, in cases with cyclic vomiting

Additional risk factors included older age, high blood pressure, smoking, and the use of aspirin

Based on the evidence that heat-shock proteins (Hsps) can exert neuroprotective effects against oxidative stress-related injury and that nutritional antioxidants are able to upregulate Hsps in neurons, use of nutritional antioxidants such as carnitine/acetyl-L-carnitine has been advocated to counteract the oxidative stress-induced brain damage in Alzheimer's disease [67, 119]

Additional studies are needed to confirm whether L-carnitine would also have this effect in people