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of Appendix A to to 29 CFR 1910.1200, the OSHA Hazard Communication Standard (HCS 2012), acute toxicity is defined specifically as adverse effects occurring following oral or dermal administration of a single dose of a substance, or multiple doses given within 24 hours, or an inhalation exposure of 4 hours

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Baseline collagen synthesis markers and elastin levels help providers predict tissue response capacity

Birchmeier et al., 2003