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At the bioactive ingredient level, salicin B, puerarin, and astragaloside A demonstrated the strongest associations with ferroptosis-related targets (103)

The cGAS-STING-dependent innate immune signaling pathway is marked by a phosphorylation cascade involving TBK1, IRF3, and STING, as well as the subsequent activation of the IFN-mediated JAK/STAT pathway, evidenced by increased phosphorylation of STAT1 [8, 31]

Ferroptosis in systemic lupus erythematosus SLE is a unique autoimmune disease characterized by the excessive production of multiple autoantibodies against the cellular components of the nucleus, cytoplasm, and cell membrane

Botta D, Franklin CC, White CC, Krejsa CM, Dabrowski MJ, Pierce RH et al