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10.3748/wjg.v28.i25.2843 [DOI] [PMC free article] [PubMed] [Google Scholar] Alberghina M., Lupo G., La Spina G., Mangiameli A., Gulisano M., Sciotto D., et al

Patients with early Leber's disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

Most patients use lipotropic injections as an adjunct to diet, exercise, and/or GLP-1 medications

So even if your diet is rich in B12 foods, you may not be absorbing it

In fact, in a toxicity study in Sprague-Dawley rats conducted with a single dose of 20 mg/kg (intramuscular, i.m.) of pentadecapeptide, no deaths or obvious abnormalities in body weight, food intake, or behavior were reported