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Description
High GSH content within astrocytes protects them from oxidative stress and preserves their ability for glutamate uptake, ion homeostasis, and immune signaling (Takahashi and Mashima, 2022)
BPC-157 has the broadest preclinical evidence base, with over 200 animal studies, but it has not been clinically validated in humans
Continued large-scale trials are needed to strengthen translational conclusions
One key change was adding a fatty acid molecule, which helps the drug to be released slowly
Impaired glutamate signaling is implicated in stress-induced cognitive deficits [23, 24]
